Original 7x10" sketch drawn and signed by Bud Blake, on his personal "Tiger" stationary.
The strip, with its cast of Tiger and his boyhood pals, was named as the year's best humor strip in 1970, 1978 and 2000 by the National Cartoonists Society. It still appears in more than 100 newspapers in 11 countries, King Features said.
The strip, which captured children's humor and charm, included Tiger, his little brother Punkinhead, his best friend Hugo and his dog Stripe.
Blake continued drawing "Tiger" until he was 85.
Before becoming a cartoonist, Blake was executive art director for an ad agency whose clients included General Motors and Goodyear. After quitting, he worked as a freelance cartoonist and on a cartoon panel called "Ever Happen to You?" He created "Tiger" in 1965, nine years after leaving the advertising firm.